SCHEMBL22136233

SCHEMBL22136233

CCCn1c(NC(C)=O)nc2cc(C(N)=O)cc(OC)c21

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22136003 0.90 STING1 (0.66) STING1
SCHEMBL22136177 0.86 STING1 (0.62) STING1
SCHEMBL22136143 0.85 STING1 (0.53) STING1
SCHEMBL19448954 0.83 STING1 (0.62) STING1
SCHEMBL19437625 0.83 STING1 (0.83) STING1
SCHEMBL29692099 0.83 STING1 (0.69) STING1
SCHEMBL28514272 0.83 STING1 (0.69) STING1
SCHEMBL22135930 0.83 STING1 (0.67) STING1
SCHEMBL19437504 0.82 STING1 (0.57) STING1
SCHEMBL29692138 0.82 STING1 (0.57) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020132549-A1 STING HETEROCYCLE AGONISTS AND USES THEREOF NIMBUS TITAN, INC. (US) 2020-06-25 WO disclosed