Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | STING1 | Q86WV6 | 8/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19437550 | 0.84 | TLR8 (0.52) | STING1TLR8 | |
| SCHEMBL19437587 | 0.82 | TLR8 (0.42) | STING1TLR8 | |
| SCHEMBL19437507 | 0.82 | TLR8 (0.45) | ALDH1A1STING1TLR8ADORA2A | |
| Bromide SCHEMBL19436512 | 0.79 | KMT2A (0.52) | STING1TLR8 | |
| SCHEMBL22135900 | 0.79 | STING1 (0.48) | STING1 | |
| Bromide SCHEMBL19437532 | 0.78 | KMT2A (0.49) | STING1TLR8 | |
| SCHEMBL22136284 | 0.78 | STING1 (0.46) | STING1 | |
| SCHEMBL19437530 | 0.76 | KDM4E (0.43) | TLR7STING1TLR8ADORA2A | |
| SCHEMBL19437498 | 0.75 | STING1 (0.53) | STING1 | |
| SCHEMBL19437547 | 0.75 | STING1 (0.44) | STING1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132549-A1 | STING HETEROCYCLE AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |