SCHEMBL22137241

SCHEMBL22137241

N#Cc1ccc(-c2ccc(-n3c4ccccc4c4cc(-c5ccccc5)ccc43)c(-c3nc(-c4ccccc4)nc(-c4cc(-c5ccc(C#N)cc5)ccc4-n4c5ccccc5c5cc(-c6ccccc6)ccc54)n3)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 12/20 0.40
ABCB1 P08183 6/20 0.40
PTGER4 P35408 1/20 0.39
ABCC1 P33527 2/20 0.37
ALDH1A3 P47895 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CLK4 Q9HAZ1 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21375301 1.00 ABCG2 (0.40) ABCG2ABCB1PTGER4ABCC1ALDH1A3
SCHEMBL20655330 0.99 ABCG2 (0.39) ABCG2ABCB1PTGER4ABCC1ALDH1A3
SCHEMBL22137242 0.99 ABCG2 (0.39) ABCG2ABCB1PTGER4ABCC1ALDH1A3
SCHEMBL24125275 0.98 ABCG2 (0.39) ABCG2ABCB1PTGER4ABCC1ALDH1A3
SCHEMBL27015814 0.98 PTGER4 (0.39) ABCG2ABCB1PTGER4ABCC1ALDH1A3
SCHEMBL21364565 0.98 ABCG2 (0.39) ABCG2ABCB1PTGER4ABCC1ALDH1A3
SCHEMBL21364846 0.98 ABCG2 (0.39) ABCG2ABCB1PTGER4ABCC1ALDH1A3
SCHEMBL21364559 0.97 ABCG2 (0.38) ABCG2ABCB1PTGER4ABCC1ALDH1A3
SCHEMBL27018929 0.97 PTGER4 (0.39) ABCG2ABCB1PTGER4ABCC1ALDH1A3
SCHEMBL20114582 0.97 PTGER4 (0.40) ABCG2ABCB1PTGER4ABCC1ALDH1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3670507-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-06-24 EP disclosed