Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 15/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.57 |
| ▸ | GRIA4 | P48058 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12513686 | 1.00 | GRIA2 (0.57) | GRIA2KCNH2GRIA4 | |
| SCHEMBL12513935 | 1.00 | GRIA2 (0.57) | GRIA2KCNH2GRIA4 | |
| SCHEMBL2213769 | 1.00 | GRIA2 (0.57) | GRIA2KCNH2GRIA4 | |
| SCHEMBL12513933 | 0.86 | GRIA2 (0.76) | GRIA2KCNH2GRIA4 | |
| SCHEMBL2214548 | 0.86 | GRIA2 (0.76) | GRIA2KCNH2GRIA4 | |
| SCHEMBL2213716 | 0.86 | GRIA2 (0.76) | GRIA2KCNH2GRIA4 | |
| SCHEMBL4101291 | 0.86 | GRIA2 (0.78) | GRIA2KCNH2GRIA4 | |
| SCHEMBL4101296 | 0.86 | GRIA2 (0.78) | GRIA2KCNH2GRIA4 | |
| SCHEMBL4101292 | 0.86 | GRIA2 (0.78) | GRIA2KCNH2GRIA4 | |
| SCHEMBL2211452 | 0.84 | GRIA2 (0.54) | GRIA2KCNH2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848695-B1 | COMPOUNDS WHICH POTENTIATE GLUTAMATE RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LTD (GB) | 2011-07-27 | — | — | EP | claimed |
| EP-1848695-B1 | COMPOUNDS WHICH POTENTIATE GLUTAMATE RECEPTOR AND USES THEREOF IN MEDICINE | GLAXO GROUP LTD (GB) | 2011-07-27 | — | — | EP | disclosed |