Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 14/20 | 0.63 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CCL2 | P13500 | 2/20 | 0.39 |
| ▸ | TAF1 | P21675 | 1/20 | 0.39 |
| ▸ | BRD2 | P25440 | 1/20 | 0.39 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.39 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.39 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | QDPR | P09417 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29455917 | 0.85 | BRD4 (0.65) | BRD4ARKCNH2CCL2TAF1 | |
| SCHEMBL22137697 | 0.85 | BRD4 (0.67) | BRD4ARKCNH2CCL2TAF1 | |
| SCHEMBL22137633 | 0.82 | BRD4 (0.52) | BRD4TAF1BRD9 | |
| SCHEMBL29455994 | 0.82 | BRD4 (0.52) | BRD4TAF1BRD9 | |
| SCHEMBL29455958 | 0.78 | BRD4 (0.62) | BRD4CCL2TAF1BRD2BRD3 | |
| SCHEMBL22137703 | 0.78 | BRD4 (0.62) | BRD4CCL2TAF1BRD2BRD3 | |
| SCHEMBL29455843 | 0.78 | BRD4 (0.49) | BRD4ARKCNH2CCL2TAF1 | |
| SCHEMBL19988067 | 0.77 | BRD4 (1.00) | BRD4ARKCNH2CCL2TAF1 | |
| SCHEMBL17477298 | 0.77 | BRD4 (1.00) | BRD4ARKCNH2CCL2TAF1 | |
| SCHEMBL19137924 | 0.77 | BRD4 (1.00) | BRD4ARKCNH2CCL2TAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132004-A1 | BET INHIBITORS FOR MODULATING DUX4 EXPRESSION IN FSHD | SAINT LOUIS UNIVERSITY (US) | 2020-06-25 | — | — | WO | disclosed |