Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.39 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23708986 | 0.98 | HPGD (0.61) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL3426748 | 0.98 | HPGD (0.61) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL23708985 | 0.98 | HPGD (0.61) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL25576093 | 0.95 | HPGD (0.52) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL2686662 | 0.85 | HPGD (0.63) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL15075709 | 0.81 | HTT (0.55) | HPGDALDH1A1TSHRHSD11B1HTT | |
| SCHEMBL25533575 | 0.81 | HTT (0.55) | HPGDALDH1A1TSHRHSD11B1HTT | |
| Hydrochloric Acid SCHEMBL30398430 | 0.81 | HPGD (0.57) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL14391353 | 0.80 | HPGD (0.75) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 | |
| SCHEMBL2686073 | 0.80 | HPGD (0.75) | HPGDALDH1A1TSHRHSD11B1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020131627-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS INHIBITORS OF FGFR TYROSINE KINASES | ARRAY BIOPHARMA INC. (US) | 2020-06-25 | — | — | WO | disclosed |