SCHEMBL2213877

SCHEMBL2213877

COCc1c[c]no1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL671575 0.75
SCHEMBL5209706 0.70
SCHEMBL314937 0.70
SCHEMBL16237641 0.64
SCHEMBL15903962 0.63 KMT2A (0.34)
SCHEMBL3140774 0.62
SCHEMBL317653 0.62
SCHEMBL2177755 0.61
SCHEMBL9393479 0.61
SCHEMBL9585 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4537315-B2 2010-09-01 JP claimed
US-7666863-B2 Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases VIROPHARMA INCORPORATED (US) 2010-02-23 US claimed
US-20070231318-A1 BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES SAHA ASHIS K 2007-10-04 US claimed
EP-1581207-A4 BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES VIROPHARMA INC (US) 2007-07-25 EP claimed
EP-1746888-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES Viropharma Incorporated (US) 2007-01-31 EP claimed
JP-2006510736-A 2006-03-30 JP claimed
WO-2005112640-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES VIROPHARMA INCORPORATED (US) 2005-12-01 WO claimed
EP-1581207-A2 BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES Viropharma Incorporated (US) 2005-10-05 EP claimed
US-20040162318-A1 Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases VIROPHARMA INCORPORATED 2004-08-19 US claimed
WO-2004041201-A2 BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES VIROPHARMA INCORPORATED (US) 2004-05-21 WO claimed
CN-114746398-A Headgroup lipid compounds and compositions for intracellular delivery of therapeutic agents 摩登纳特斯有限公司 2022-07-12 CN disclosed
EP-3271340-B1 SALTS OF N-(1,3,4-OXADIAZOL-2-YL) ARYL CARBOXYLIC ACID AMIDES AND USE OF SAME AS HERBICIDES BAYER CROPSCIENCE AG (DE) 2019-10-02 EP disclosed
US-8765789-B2 2-pyridinecarboxamide derivatives MSD K.K. (JP) 2014-07-01 US disclosed
US-20140045890-A1 NOVEL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-13 US disclosed
EP-2691386-A1 QUINOLINE DERIVATIVES AS FUNGICIDES Syngenta Participations AG (CH) 2014-02-05 EP disclosed
WO-1998050385-A1 SUBSTITUTED 1,2,4-TRIAZOLO[3,4-a]PHTHALAZINE DERIVATIVES AS GABA ALPHA 5 LIGANDS MERCK SHARP & DOHME LIMITED (GB) 1998-11-12 WO disclosed
EP-0579810-A1 NOVEL PYRETHRINOID ESTERS DERIVED FROM ISOXAZOLIC OR ISOTHIAZOLIC ALCOHOL, PREPARATION METHOD THEREFOR AND USE THEREOF AS PESTICIDES ROUSSEL UCLAF (FR) 1994-01-26 EP disclosed
WO-1993016054-A1 NOVEL PYRETHRINOID ESTERS DERIVED FROM ISOXAZOLIC OR ISOTHIAZOLIC ALCOHOL, PREPARATION METHOD THEREFOR AND USE THEREOF AS PESTICIDES ROUSSEL-UCLAF (FR) 1993-08-19 WO disclosed
US-4797148-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1989-01-10 US disclosed
EP-0224823-A2 Quinoline derivatives and their use in combating unwanted plant growth BASF Aktiengesellschaft (DE) 1987-06-10 EP disclosed