Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 16/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.46 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.44 |
| ▸ | TTK | P33981 | 3/20 | 0.43 |
| ▸ | LCK | P06239 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22124586 | 1.00 | PTK6 (0.50) | PTK6AURKBMAPKAPK5TTKLCK | |
| SCHEMBL22124536 | 1.00 | PTK6 (0.50) | PTK6AURKBMAPKAPK5TTKLCK | |
| SCHEMBL30177640 | 1.00 | PTK6 (0.50) | PTK6AURKBMAPKAPK5TTKLCK | |
| SCHEMBL22123870 | 0.97 | PTK6 (0.48) | PTK6AURKBMAPKAPK5TTKLCK | |
| SCHEMBL30171842 | 0.97 | PTK6 (0.48) | PTK6AURKBMAPKAPK5TTKLCK | |
| SCHEMBL22124445 | 0.97 | PTK6 (0.48) | PTK6AURKBMAPKAPK5TTKLCK | |
| SCHEMBL22139106 | 0.97 | PTK6 (0.48) | PTK6AURKBMAPKAPK5TTKLCK | |
| Hydrochloric Acid SCHEMBL25174648 | 0.96 | PTK6 (0.48) | PTK6AURKBMAPKAPK5TTKLCK | |
| Hydrochloric Acid SCHEMBL30171575 | 0.96 | PTK6 (0.48) | PTK6AURKBMAPKAPK5TTKLCK | |
| Hydrochloric Acid SCHEMBL30171912 | 0.96 | PTK6 (0.48) | PTK6AURKBMAPKAPK5TTKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898630-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2023-05-10 | — | — | EP | disclosed |
| EP-3898629-B1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020127075-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020126954-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020126956-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |