Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22140656 | 0.89 | POLB (0.60) | MAPTMEN1KMT2APOLBHPGD | |
| SCHEMBL22140795 | 0.87 | MAPT (0.51) | MAPTMEN1KMT2APOLBHPGD | |
| SCHEMBL12181279 | 0.81 | KMT2A (0.62) | MAPTMEN1KMT2APOLBHPGD | |
| SCHEMBL22140773 | 0.81 | MAPT (0.51) | MAPTMEN1KMT2APOLBHPGD | |
| SCHEMBL12324448 | 0.78 | KDM4E (0.58) | MAPTMEN1KMT2APOLBHPGD | |
| SCHEMBL16260462 | 0.78 | KMT2A (0.58) | MAPTMEN1KMT2APOLBHPGD | |
| SCHEMBL22140757 | 0.77 | PTPN1 (0.53) | MAPTMEN1KMT2APOLBHPGD | |
| SCHEMBL29709994 | 0.77 | POLB (0.53) | MAPTMEN1KMT2APOLBHPGD | |
| SCHEMBL22140800 | 0.76 | MEN1 (0.57) | MAPTMEN1KMT2APOLBHPGD | |
| SCHEMBL22140798 | 0.76 | MEN1 (0.57) | MAPTMEN1KMT2APOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020127165-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-06-25 | — | — | WO | disclosed |