Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22140757 | 0.90 | PTPN1 (0.53) | PTPN1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL22140904 | 0.84 | PTPN1 (0.53) | PTPN1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL22140784 | 0.84 | PTPN1 (0.47) | PTPN1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL22140929 | 0.77 | KDM4E (0.42) | PTPN1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL22140656 | 0.76 | POLB (0.60) | PTPN1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL12181279 | 0.75 | KMT2A (0.62) | PTPN1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL22140753 | 0.74 | CYP19A1 (0.47) | PTPN1MAPTKDM4EALDH1A1HTT | |
| SCHEMBL22140756 | 0.74 | MAPT (0.51) | PTPN1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL22140762 | 0.74 | MAPT (0.51) | PTPN1KMT2AMAPTPOLBKDM4E | |
| SCHEMBL12324448 | 0.72 | KDM4E (0.58) | PTPN1KMT2AMAPTPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020127165-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-06-25 | — | — | WO | disclosed |