Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 14/20 | 0.50 |
| ▸ | TTK | P33981 | 3/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.42 |
| ▸ | MAPKAPK5 | Q8IW41 | 3/20 | 0.41 |
| ▸ | LCK | P06239 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22124594 | 0.98 | PTK6 (0.48) | PTK6TTKAURKBMAPKAPK5LCK | |
| Formic Acid SCHEMBL22123452 | 0.95 | PTK6 (0.46) | PTK6TTKAURKBMAPKAPK5LCK | |
| SCHEMBL22142737 | 0.94 | PTK6 (0.50) | PTK6TTKAURKBMAPKAPK5LCK | |
| SCHEMBL28919797 | 0.94 | PTK6 (0.50) | PTK6TTKAURKBMAPKAPK5LCK | |
| SCHEMBL22125054 | 0.93 | PTK6 (0.49) | PTK6TTKAURKBMAPKAPK5LCK | |
| SCHEMBL30177744 | 0.93 | PTK6 (0.46) | PTK6TTKAURKBMAPKAPK5LCK | |
| SCHEMBL22124003 | 0.93 | PTK6 (0.46) | PTK6TTKAURKBMAPKAPK5LCK | |
| SCHEMBL22123950 | 0.92 | PTK6 (0.49) | PTK6TTKAURKBMAPKAPK5LCK | |
| SCHEMBL22139115 | 0.92 | PTK6 (0.48) | PTK6TTKAURKBMAPKAPK5LCK | |
| SCHEMBL22124431 | 0.92 | PTK6 (0.48) | PTK6TTKAURKBMAPKAPK5LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898629-B1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |
| WO-2020127075-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |