SCHEMBL221428

SCHEMBL221428

CCC(C#N)CCN=NCCC(C#N)CC

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11779260 0.88 TSHR (0.30) TSHR
SCHEMBL6053395 0.83
SCHEMBL17985103 0.81
SCHEMBL15309950 0.81 TSHR (0.41) TSHR
SCHEMBL17985118 0.78
SCHEMBL17985117 0.78
SCHEMBL7098261 0.78
SCHEMBL17985130 0.76
SCHEMBL17985133 0.76
SCHEMBL464424 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3371148-B1 USE AND PREPARATION OF REGULATORS FOR CONTROLLING LINEAR AND PSEUDO-RING EXPANSION POLYMERIZATION OF VINYL MONOMERS DISPOLTEC B V (NL) 2021-05-05 EP disclosed
US-10947325-B2 Regulators for controlling linear and pseudo-ring expansion polymerization of vinyl monomers DISPOLTEC B.V. (NL) 2021-03-16 US disclosed
US-20180334516-A1 REGULATORS FOR CONTROLLING LINEAR AND PSEUDO-RING EXPANSION POLYMERIZATION OF VINYL MONOMERS DISPOLTEC B.V. (NL) 2018-11-22 US disclosed
EP-3371148-A1 REGULATORS FOR CONTROLLING LINEAR AND PSEUDO-RING EXPANSION POLYMERIZATION OF VINYL MONOMERS Dispoltec B.V. (NL) 2018-09-12 EP disclosed
WO-2017076992-A1 REGULATORS FOR CONTROLLING LINEAR AND PSEUDO-RING EXPANSION POLYMERIZATION OF VINYL MONOMERS DISPOLTEC B.V. (NL) 2017-05-11 WO disclosed
US-8232345-B2 Method of making salt-sensitive binders and nonwoven webs CELANESE INTERNATIONAL CORPORATION (US) 2012-07-31 US disclosed
US-8088252-B2 Salt-sensitive cationic polymeric binders for nonwoven webs and method of making the same CELANESE INTERNATIONAL CORPORATION 2012-01-03 US disclosed
US-7989545-B2 Salt-sensitive binders for nonwoven webs and method of making same Celanese International Corporations (US) 2011-08-02 US disclosed
US-20110146927-A1 Method of making salt-sensitive binders and nonwoven webs PROFOUND MEDICAL INC. (CA) 2011-06-23 US disclosed
EP-2272880-A1 Salt-sensitive binders for nonwoven webs and method of making same Celanese International Corporation (US) 2011-01-12 EP disclosed
EP-0625999-A1 CROSSLINKABLE SURFACE COATINGS. JOHNSON & SON INC S C (US) 1994-11-30 EP disclosed
EP-0482027-B1 POLYMERIC THICKENERS AND METHODS OF PRODUCING THE SAME JOHNSON & SON INC S C (US) 1994-11-09 EP disclosed
WO-1993016133-A2 CROSSLINKABLE SURFACE COATINGS S.C. JOHNSON & SON, INC. (US) 1993-08-19 WO disclosed
EP-0482027-A4 POLYMERIC THICKENERS AND METHODS OF PRODUCING THE SAME 1992-08-19 EP disclosed
EP-0482027-A1 POLYMERIC THICKENERS AND METHODS OF PRODUCING THE SAME. JOHNSON & SON INC S C (US) 1992-04-29 EP disclosed
US-5073591-A Polymerization of unsaturated acidic monomer, reacting with amino compound; ph adjustment S. C. JOHNSON & SON, INC. (US) 1991-12-17 US disclosed
US-5053448-A Emulsion polymerizing acid moiety-containing monomer and ethyleneically unsaturated monomer, adding amino moiety containing monomer S. C. JOHNSON & SON, INC. (US) 1991-10-01 US disclosed
WO-1991001336-A1 POLYMERIC THICKENERS AND METHODS OF PRODUCING THE SAME S.C. JOHNSON & SON, INC. (US) 1991-02-07 WO disclosed
US-4230844-A POLYMERIZING (METH-)ACRYLIC ACID AND AN ACRYLATE MODIFIED POLYOXYETHYLENE GLYCOL E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-10-28 US disclosed
US-4138381-A A,B-UNSATURATED ACID-ALKYL ACRYLATE-POLYETHER ACRYLATE TERPOLYMER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180334516-A1 REGULATORS FOR CONTROLLING LINEAR AND PSEUDO-RING EXPANSION POLYMERIZATION OF VINYL MONOMERS ORC3, RPS27L, OXGR1 TSHR 3855/4885
US-10947325-B2 Regulators for controlling linear and pseudo-ring expansion polymerization of vinyl monomers ORC3, RPS27L, OXGR1 TSHR 3855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.