Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 17/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.36 |
| ▸ | LCK | P06239 | 6/20 | 0.36 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24910616 | 0.94 | PTK6 (0.44) | PTK6AURKBLCKMAPKAPK5TTK | |
| SCHEMBL22123982 | 0.93 | PTK6 (0.44) | PTK6AURKBLCKMAPKAPK5TTK | |
| SCHEMBL22139155 | 0.91 | PTK6 (0.42) | PTK6AURKBLCKMAPKAPK5TTK | |
| SCHEMBL22124986 | 0.91 | PTK6 (0.42) | PTK6AURKBLCKMAPKAPK5TTK | |
| Formic Acid SCHEMBL30171925 | 0.91 | PTK6 (0.42) | PTK6AURKBLCKMAPKAPK5TTK | |
| Formic Acid SCHEMBL30171608 | 0.89 | PTK6 (0.40) | PTK6AURKBLCKMAPKAPK5TTK | |
| SCHEMBL22124078 | 0.87 | PTK6 (0.43) | PTK6AURKBLCKMAPKAPK5TTK | |
| SCHEMBL24939258 | 0.86 | PTK6 (0.41) | PTK6AURKBLCKMAPKAPK5TTK | |
| SCHEMBL24870896 | 0.86 | PTK6 (0.46) | PTK6AURKBLCKTTK | |
| SCHEMBL22142988 | 0.86 | PTK6 (0.44) | PTK6AURKBLCKTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020127075-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |