Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 12/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.38 |
| ▸ | LCK | P06239 | 4/20 | 0.36 |
| ▸ | QPCT | Q16769 | 3/20 | 0.36 |
| ▸ | BCL9 | O00512 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24870782 | 0.95 | PTK6 (0.43) | PTK6AURKBLCKQPCTBCL9 | |
| SCHEMBL22139163 | 0.94 | PTK6 (0.44) | PTK6AURKBLCKQPCTBCL9 | |
| SCHEMBL22142817 | 0.92 | PTK6 (0.44) | PTK6AURKBLCKQPCTBCL9 | |
| SCHEMBL22142746 | 0.90 | PTK6 (0.47) | PTK6AURKBLCKQPCTFGFR3 | |
| SCHEMBL30183424 | 0.87 | PTK6 (0.38) | PTK6AURKBLCKQPCTBCL9 | |
| SCHEMBL22122833 | 0.87 | PTK6 (0.38) | PTK6AURKBLCKQPCTBCL9 | |
| SCHEMBL30183124 | 0.87 | PTK6 (0.46) | PTK6AURKBLCKFGFR3TTK | |
| SCHEMBL22123102 | 0.87 | PTK6 (0.38) | PTK6AURKBLCKQPCTBCL9 | |
| SCHEMBL22154799 | 0.86 | PTK6 (0.33) | PTK6NAMPTTTKMAPKAPK5 | |
| SCHEMBL24870932 | 0.86 | PTK6 (0.41) | PTK6AURKBLCKQPCTBCL9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898629-B1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |
| WO-2020127075-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |