SCHEMBL2214461 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	GCK	P35557	13/20	0.65

▸	MEN1	O00255	1/20	0.39

▸	NPC1	O15118	1/20	0.39

▸	MGAM	O43451	1/20	0.39

▸	ALDH1A1	P00352	1/20	0.39

▸	GAA	P10253	1/20	0.39

▸	MAPT	P10636	1/20	0.39

▸	SI	P14410	1/20	0.39

▸	RAB9A	P51151	1/20	0.39

▸	KMT2A	Q03164	1/20	0.39

▸	SMN1; SMN2	Q16637	1/20	0.39

▸	MGAM2	Q2M2H8	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2642383	0.83	GCK (0.48)	GCK
SCHEMBL2213982	0.82	GCK (0.63)	GCKMEN1NPC1MGAMALDH1A1
SCHEMBL2213370	0.80	GCK (0.73)	GCKMEN1NPC1MGAMALDH1A1
SCHEMBL2643024	0.79	GCK (1.00)	GCKSMN1; SMN2
SCHEMBL2213443	0.79	GCK (0.71)	GCKMEN1NPC1MGAMALDH1A1
SCHEMBL2213619	0.76	GCK (0.72)	GCK
SCHEMBL2210526	0.73	GCK (0.67)	GCK
SCHEMBL2212679	0.71	GCK (0.75)	GCK
SCHEMBL2250207	0.71	GCK (0.59)	GCKNPC1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL2212557	0.71	GCK (0.73)	GCKNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1598349-B1	NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES	MSD KK (JP)	2011-07-27	—	—	EP	claimed