⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13356464 | 0.65 | — | — | |
| SCHEMBL16200056 | 0.60 | — | — | |
| SCHEMBL22868426 | 0.59 | — | — | |
| SCHEMBL14320129 | 0.55 | — | — | |
| SCHEMBL12191404 | 0.50 | DYRK1A (0.35) | — | |
| SCHEMBL14043820 | 0.49 | — | — | |
| SCHEMBL11632178 | 0.49 | — | — | |
| SCHEMBL9026991 | 0.49 | — | — | |
| Tetrabromobenzotriazole SCHEMBL16463781 | 0.48 | CSNK2A1 (1.00) | — | |
| SCHEMBL13912864 | 0.43 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11072619-B2 | Pyrazole[1,5-a] pyrimidine derivatives as kinase JAK inhibitors | CELON PHARMA S.A. (PL) | 2021-07-27 | — | — | US | disclosed |
| US-20200199128-A1 | PYRAZOLE[1,5-A]PYRIMIDINE DERIVATIVES AS KINASE JAK INHIBITORS | CELON PHARMA S.A. (PL) | 2020-06-25 | — | — | US | disclosed |