Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12240915 | 1.00 | DPP4 (0.48) | DPP4DPP8DPP9SLC1A3SLC1A2 | |
| SCHEMBL10925103 | 1.00 | DPP4 (0.48) | DPP4DPP8DPP9SLC1A3SLC1A2 | |
| SCHEMBL160632 | 0.85 | SLC7A5 (0.58) | DPP4DPP8DPP9SLC1A3SLC1A2 | |
| SCHEMBL10074959 | 0.85 | SLC7A5 (0.58) | DPP4DPP8DPP9SLC1A3SLC1A2 | |
| SCHEMBL5257074 | 0.85 | DPP4 (0.48) | DPP4DPP8DPP9SLC1A3SLC1A2 | |
| SCHEMBL17449974 | 0.85 | DPP4 (0.48) | DPP4DPP8DPP9SLC1A3SLC1A2 | |
| SCHEMBL160633 | 0.85 | SLC7A5 (0.58) | DPP4DPP8DPP9SLC1A3SLC1A2 | |
| SCHEMBL8703272 | 0.83 | MME (0.49) | DPP4SLC1A3SLC1A2SLC1A1MME | |
| SCHEMBL26903695 | 0.83 | MME (0.49) | DPP4SLC1A3SLC1A2SLC1A1MME | |
| SCHEMBL5222079 | 0.83 | SLC1A3 (0.47) | DPP4DPP8DPP9SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020131283-A1 | ANALOGS THAT TARGET MITOCHONDRIAL DISEASES | STEALTH BIOTHERAPEUTICS CORP. (MC) | 2020-06-25 | — | — | WO | disclosed |