Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.53 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.53 |
| ▸ | ABL1 | P00519 | 2/20 | 0.53 |
| ▸ | CDK7 | P50613 | 2/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.53 |
| ▸ | BTK | Q06187 | 1/20 | 0.53 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | GRK5 | P34947 | 2/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | FLT1 | P17948 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31329927 | 0.76 | ABL1 (0.53) | CSNK1A1CLK4DYRK1BABL1CDK7 | |
| SCHEMBL10138768 | 0.64 | ABL1 (0.41) | CSNK1A1CLK4DYRK1BABL1CDK7 | |
| SCHEMBL14141984 | 0.64 | ABL1 (0.45) | CSNK1A1CLK4DYRK1BABL1CDK7 | |
| SCHEMBL4071831 | 0.63 | RET (0.43) | CSNK1A1CLK4DYRK1BABL1CDK7 | |
| SCHEMBL17804189 | 0.63 | ABL1 (0.40) | CSNK1A1CLK4DYRK1BABL1CDK7 | |
| SCHEMBL557100 | 0.58 | ABL1 (0.36) | CSNK1A1CLK4DYRK1BABL1CDK7 | |
| SCHEMBL10830676 | 0.58 | ABL1 (0.36) | CSNK1A1CLK4DYRK1BABL1CDK7 | |
| SCHEMBL1187755 | 0.57 | KDM4E (0.64) | CSNK1A1CLK4DYRK1BABL1CDK7 | |
| Bromide SCHEMBL1188167 | 0.56 | KDM4E (0.62) | CSNK1A1CLK4DYRK1BABL1CDK7 | |
| SCHEMBL16946874 | 0.56 | PIM1 (0.41) | CSNK1A1CLK4DYRK1BABL1CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020125759-A1 | COMPOUND AS WNT SIGNAL PATHWAY INHIBITOR AND MEDICAL USE THEREOF | 汇瀚医疗科技有限公司 | 2020-06-25 | — | — | WO | disclosed |