⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22991874 | 0.79 | — | — | |
| SCHEMBL4712261 | 0.72 | NEK2 (0.33) | — | |
| SCHEMBL24795248 | 0.67 | — | — | |
| SCHEMBL12853565 | 0.67 | — | — | |
| SCHEMBL13576365 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL456109 | 0.65 | — | — | |
| SCHEMBL26634436 | 0.63 | — | — | |
| SCHEMBL22117676 | 0.63 | — | — | |
| SCHEMBL22307714 | 0.63 | — | — | |
| SCHEMBL17624384 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339902-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | C4 THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | US | disclosed |
| WO-2020131674-A1 | 7-((3,5-DIMETHOXYPHENYL)AMINO)QUINOXALINE DERIVATIVES AS FGFR INHIBITORS FOR TREATING CANCER | ARRAY BIOPHARMA INC. (US) | 2020-06-25 | — | — | WO | disclosed |