Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | CDK1 | P06493 | 3/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL823082 | 0.78 | DYRK1A (0.50) | DYRK1ACCNT1PIM1CCNA2CDK2 | |
| SCHEMBL1892910 | 0.77 | DYRK1A (0.49) | DYRK1ACCNT1PIM1CCNA2CDK2 | |
| SCHEMBL20674192 | 0.77 | DYRK1A (0.49) | DYRK1ACCNT1PIM1CCNA2CDK2 | |
| SCHEMBL16307577 | 0.77 | DYRK1A (0.49) | DYRK1ACCNT1PIM1CCNA2CDK2 | |
| SCHEMBL15792325 | 0.77 | DYRK1A (0.49) | DYRK1ACCNT1PIM1CCNA2CDK2 | |
| SCHEMBL30503547 | 0.77 | DYRK1A (0.49) | DYRK1ACCNT1PIM1CCNA2CDK2 | |
| SCHEMBL30731192 | 0.77 | DYRK1A (0.49) | DYRK1ACCNT1PIM1CCNA2CDK2 | |
| SCHEMBL14197833 | 0.77 | DYRK1A (0.49) | DYRK1ACCNT1PIM1CCNA2CDK2 | |
| SCHEMBL27439703 | 0.76 | DYRK1A (0.59) | DYRK1ACCNT1PIM1CCNA2CDK2 | |
| SCHEMBL23104761 | 0.74 | DYRK1A (0.47) | DYRK1ACCNT1PIM1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020125673-A1 | INFLUENZA VIRUS REPLICATION INHIBITOR, INTERMEDIATE AND USE THEREOF | 南京药石科技股份有限公司 | 2020-06-25 | — | — | WO | disclosed |