Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22149379 | 0.82 | IGF1R (0.33) | IGF1R | |
| SCHEMBL22149401 | 0.78 | IGF1R (0.35) | IGF1RCYP1A2IRAK4 | |
| SCHEMBL24765705 | 0.73 | TTK (0.47) | IGF1RCYP1A2IRAK4 | |
| SCHEMBL25783428 | 0.73 | TTK (0.47) | IGF1RCYP1A2IRAK4 | |
| SCHEMBL22899524 | 0.72 | LCK (0.46) | IGF1RIRAK4 | |
| SCHEMBL22149374 | 0.72 | IGF1R (0.39) | IGF1RCYP1A2IRAK4TGFBR1 | |
| SCHEMBL24766244 | 0.71 | LCK (0.48) | IGF1RIRAK4 | |
| SCHEMBL22149376 | 0.71 | IGF1R (0.34) | IGF1RCYP1A2 | |
| SCHEMBL22149366 | 0.70 | IGF1R (0.35) | IGF1RCYP1A2IRAK4 | |
| SCHEMBL22149169 | 0.70 | IGF1R (0.38) | IGF1RCYP1A2IRAK4TGFBR1TGFBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020125673-A1 | INFLUENZA VIRUS REPLICATION INHIBITOR, INTERMEDIATE AND USE THEREOF | 南京药石科技股份有限公司 | 2020-06-25 | — | — | WO | disclosed |