SCHEMBL22149999

SCHEMBL22149999

CCc1nc(C)oc1C(=O)Nc1nc2cc(C(N)=O)cc(OC)c2n1C/C=C/Cn1c(NC(=O)c2oc(C)nc2CC)nc2cc(C(N)=O)cc(OC)c21

nearest known ligand 0.88

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29684551 1.00 STING1 (0.88) STING1
SCHEMBL22151701 0.97 STING1 (0.83) STING1
SCHEMBL22149976 0.96 STING1 (0.81) STING1
SCHEMBL29684574 0.96 STING1 (0.81) STING1
SCHEMBL28751727 0.96 STING1 (0.81) STING1
SCHEMBL22150351 0.94 STING1 (0.84) STING1
SCHEMBL28751740 0.94 STING1 (0.84) STING1
SCHEMBL22151629 0.94 STING1 (0.94) STING1
SCHEMBL22121424 0.94 STING1 (1.00) STING1
SCHEMBL22121428 0.94 STING1 (1.00) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020132582-A1 STING AGONISTS AND USES THEREOF NIMBUS TITAN, INC. (US) 2020-06-25 WO disclosed