SCHEMBL221501

SCHEMBL221501

O=C(Cl)OC1CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11422188 1.00 SERPINE1 (0.37)
SCHEMBL11423412 1.00 SERPINE1 (0.37)
SCHEMBL9275379 1.00 SERPINE1 (0.37)
SCHEMBL21496381 0.92 SERPINE1 (0.33)
SCHEMBL393224 0.88
SCHEMBL67220 0.88
SCHEMBL7418958 0.88 EPHX1 (0.41)
SCHEMBL6112267 0.87 CYP19A1 (0.42)
SCHEMBL21291237 0.87 SERPINE1 (0.31)
SCHEMBL134211 0.87 CYP19A1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 507 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119462650-A Non-goetide method for synthesizing nylon 沈阳药科大学 2025-02-18 CN claimed
CN-119431312-A Enzymatic serum albumin fluorescent probe and synthesis and application thereof 河北大学 2025-02-14 CN claimed
CN-119192053-A Fluorescent probe for butyrylcholine esterase detection and preparation method and application thereof 河南省农业科学院农产品质量安全研究所 2024-12-27 CN claimed
CN-118561777-A Near-infrared small molecule fluorescent probe and synthetic method and application thereof 青岛科技大学 2024-08-30 CN claimed
CN-117700426-A Podophyllotoxin derivative and preparation method and application thereof 马鞍山市食品药品检验和药品不良反应监测中心 2024-03-15 CN claimed
CN-109956906-B Preparation method of key intermediate of oxalagogri 奥锐特药业股份有限公司 2021-01-29 CN claimed
CN-109956906-A A kind of preparation method for disliking La Geli key intermediate 奥锐特药业股份有限公司 2019-07-02 CN claimed
EP-1754705-A2 Antagonists for treatment of CD11/CD18 adhesion receptor mediated disorders Genentech, Inc. (US) 2007-02-21 EP claimed
EP-0494146-B1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE OR RACEMIC CYCLOPROPANE-CARBOXYLIC-ACID CHLORIDES CHINOIN GYOGYSZER ES VEGYESZET (HU) 1995-10-25 EP claimed
EP-0434357-A2 Fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-06-26 EP claimed
JP-1157964-A None JP disclosed
US-12630562-B2 Piperidylurea compounds and methods of use thereof ARCUS BIOSCIENCES, INC. (US) 2026-05-19 US disclosed
CN-122036749-A Aryl morpholine ring compound and application thereof 成都赜灵生物医药科技股份有限公司 2026-05-15 CN disclosed
CN-121949325-A (Pyrazolo [3,4-d ] pyrimidine-1-yl) cyclopropyl ketone compound and preparation method and application thereof 广东药科大学 2026-05-01 CN disclosed
EP-4711365-A1 THIAZOLE DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shanghai Hansoh Biomedical Co., Ltd. (CN) 2026-03-18 EP disclosed
US-3995054-A MITICIDES ZOECON CORPORATION (US) 1976-11-30 US disclosed
US-3966747-A NARCOTIC AGONIST ANDOR ANTAGONIST ACTIVITY BRISTOL-MYERS COMPANY (US) 1976-06-29 US disclosed
US-3959290-A ANALGESICS, NARCOTIC ANTAGONISTS BRISTOL-MYERS COMPANY (US) 1976-05-25 US disclosed
US-3957849-A MITICIDES ZOECON CORPORATION (US) 1976-05-18 US disclosed
US-3951987-A PSYCHOSEDATIVE HOFFMANN-LA ROCHE INC. (US) 1976-04-20 US disclosed