Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22150373 | 1.00 | KMT2A (0.63) | KMT2AMEN1TSHRALDH1A1EPHX2 | |
| SCHEMBL3713361 | 0.96 | KMT2A (0.57) | KMT2AMEN1TSHRALDH1A1EPHX2 | |
| SCHEMBL18908735 | 0.92 | KMT2A (0.73) | KMT2AMEN1TSHRALDH1A1EPHX2 | |
| SCHEMBL10447931 | 0.92 | KMT2A (0.73) | KMT2AMEN1TSHRALDH1A1EPHX2 | |
| SCHEMBL18908674 | 0.92 | KMT2A (0.73) | KMT2AMEN1TSHRALDH1A1EPHX2 | |
| SCHEMBL12387741 | 0.90 | KMT2A (0.69) | KMT2AMEN1TSHRALDH1A1EPHX2 | |
| SCHEMBL12112072 | 0.89 | TSHR (0.54) | KMT2AMEN1TSHRALDH1A1EPHX2 | |
| SCHEMBL21771221 | 0.89 | KMT2A (0.63) | KMT2AMEN1TSHREPHX2CYP2D6 | |
| SCHEMBL19050851 | 0.89 | KMT2A (0.63) | KMT2AMEN1TSHREPHX2CYP2D6 | |
| SCHEMBL22790865 | 0.88 | MEN1 (0.54) | KMT2AMEN1TSHRALDH1A1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081759-A1 | BIFUNCTIONAL PI3K-ALPHA INHIBITORS AND USES THEREOF | RELAY THERAPEUTICS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |