Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 17/20 | 0.46 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22150535 | 0.96 | STING1 (0.44) | STING1ITKKDM4ENPSR1 | |
| SCHEMBL22150391 | 0.93 | STING1 (0.42) | STING1ITKKDM4ENPSR1 | |
| SCHEMBL22121460 | 0.92 | STING1 (0.56) | STING1 | |
| SCHEMBL22121457 | 0.92 | STING1 (0.56) | STING1 | |
| SCHEMBL22121504 | 0.92 | STING1 (0.59) | STING1 | |
| SCHEMBL22121503 | 0.92 | STING1 (0.59) | STING1 | |
| SCHEMBL22150538 | 0.91 | STING1 (0.48) | STING1 | |
| SCHEMBL22121332 | 0.89 | STING1 (0.40) | STING1 | |
| SCHEMBL22150532 | 0.89 | STING1 (0.40) | STING1ITKKDM4ENPSR1 | |
| SCHEMBL22150506 | 0.88 | STING1 (0.53) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |