Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 20/20 | 0.63 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28597016 | 0.93 | STING1 (0.71) | STING1TBK1 | |
| SCHEMBL19451659 | 0.93 | STING1 (0.71) | STING1TBK1 | |
| SCHEMBL22150398 | 0.91 | STING1 (0.53) | STING1TBK1 | |
| SCHEMBL22150362 | 0.91 | STING1 (0.68) | STING1TBK1 | |
| SCHEMBL22150399 | 0.90 | STING1 (0.60) | STING1TBK1CYP3A4 | |
| SCHEMBL22134997 | 0.89 | STING1 (0.67) | STING1TBK1 | |
| SCHEMBL29702138 | 0.87 | STING1 (0.81) | STING1TBK1 | |
| SCHEMBL19451632 | 0.87 | STING1 (0.81) | STING1TBK1 | |
| SCHEMBL19451688 | 0.86 | STING1 (0.70) | STING1TBK1 | |
| SCHEMBL28613424 | 0.86 | STING1 (0.70) | STING1TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |