Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 19/20 | 0.66 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.66 |
| ▸ | IRF3 | Q14653 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19437609 | 0.89 | STING1 (0.82) | STING1TBK1 | |
| SCHEMBL19451506 | 0.86 | STING1 (0.90) | STING1TBK1 | |
| SCHEMBL31494201 | 0.86 | STING1 (0.90) | STING1TBK1 | |
| SCHEMBL22520079 | 0.84 | STING1 (0.63) | STING1TBK1IRF3 | |
| SCHEMBL22150368 | 0.84 | STING1 (0.73) | STING1TBK1 | |
| SCHEMBL22150068 | 0.84 | STING1 (0.63) | STING1TBK1 | |
| SCHEMBL24467521 | 0.83 | STING1 (0.84) | STING1TBK1 | |
| SCHEMBL19451507 | 0.83 | STING1 (0.84) | STING1TBK1 | |
| SCHEMBL22151664 | 0.83 | STING1 (0.82) | STING1TBK1 | |
| Trifluoroacetic Acid SCHEMBL29619904 | 0.81 | STING1 (0.80) | STING1TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |