Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22153186 | 0.80 | PDE10A (0.35) | PDE10APDCD1CD274ACACBPRKAB2 | |
| SCHEMBL15260161 | 0.74 | PDE10A (0.44) | PDE10ACCNCCDK8MAP4K4 | |
| SCHEMBL12525723 | 0.73 | KMT2A (0.61) | KMT2A | |
| SCHEMBL22153203 | 0.72 | PDE10A (0.46) | PDE10ACCNCCDK8PDE4BKMT2A | |
| SCHEMBL13155045 | 0.70 | PDE10A (0.47) | PDE10ACCNCCDK8 | |
| SCHEMBL25226170 | 0.69 | PDE10A (0.42) | PDE10ACCNCCDK8MAP4K4ACACB | |
| SCHEMBL20073609 | 0.69 | GRIN2B (0.45) | PDE10ACCNCCDK8MAP4K4ACACB | |
| SCHEMBL31015153 | 0.69 | KDM4E (0.50) | PDE10ACCNCCDK8PDCD1CD274 | |
| SCHEMBL29883765 | 0.69 | GRIN2B (0.45) | PDE10ACCNCCDK8MAP4K4ACACB | |
| SCHEMBL17624443 | 0.69 | CCNC (0.41) | PDE10ACCNCCDK8MAP4K4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020125627-A1 | PHENYLPYRROLIDINE COMPOUND AND USE THEREOF | 湖北生物医药产业技术研究院有限公司 | 2020-06-25 | — | — | WO | disclosed |