Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 14/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.39 |
| ▸ | CDK9 | P50750 | 4/20 | 0.39 |
| ▸ | LCK | P06239 | 5/20 | 0.35 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL30177718 | 0.97 | PTK6 (0.42) | PTK6AURKBCCNT1CDK9LCK | |
| SCHEMBL22124393 | 0.95 | PTK6 (0.43) | PTK6AURKBCCNT1CDK9LCK | |
| SCHEMBL22125166 | 0.95 | PTK6 (0.43) | PTK6AURKBCCNT1CDK9LCK | |
| SCHEMBL30171641 | 0.95 | PTK6 (0.43) | PTK6AURKBCCNT1CDK9LCK | |
| SCHEMBL22124089 | 0.95 | PTK6 (0.43) | PTK6AURKBCCNT1CDK9LCK | |
| SCHEMBL30171923 | 0.95 | PTK6 (0.43) | PTK6AURKBCCNT1CDK9LCK | |
| SCHEMBL30177866 | 0.95 | PTK6 (0.43) | PTK6AURKBCCNT1CDK9LCK | |
| Hydrochloric Acid SCHEMBL25176491 | 0.94 | PTK6 (0.42) | PTK6AURKBCCNT1CDK9LCK | |
| SCHEMBL22125387 | 0.94 | PTK6 (0.52) | PTK6AURKBLCK | |
| SCHEMBL22124167 | 0.94 | PTK6 (0.42) | PTK6AURKBCCNT1CDK9LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020126952-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |