Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26351482 | 1.00 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2LTA4HTPSAB1 | |
| SCHEMBL24252193 | 0.90 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2LTA4HTPSAB1 | |
| SCHEMBL28948135 | 0.88 | SMN1; SMN2 (0.46) | NPC1RAB9ASMN1; SMN2LTA4HTPSAB1 | |
| SCHEMBL25602956 | 0.85 | SMN1; SMN2 (0.47) | NPC1RAB9ASMN1; SMN2LTA4HTPSAB1 | |
| SCHEMBL27068058 | 0.85 | SMN1; SMN2 (0.47) | NPC1RAB9ASMN1; SMN2LTA4HTPSAB1 | |
| SCHEMBL24279731 | 0.84 | SMN1; SMN2 (0.45) | NPC1RAB9ASMN1; SMN2LTA4HTPSAB1 | |
| SCHEMBL23054325 | 0.84 | SMN1; SMN2 (0.45) | NPC1RAB9ASMN1; SMN2LTA4HTPSAB1 | |
| SCHEMBL23054326 | 0.84 | SMN1; SMN2 (0.45) | NPC1RAB9ASMN1; SMN2LTA4HTPSAB1 | |
| SCHEMBL15382668 | 0.84 | SMN1; SMN2 (0.45) | NPC1RAB9ASMN1; SMN2LTA4HTPSAB1 | |
| SCHEMBL18499692 | 0.84 | SMN1; SMN2 (0.45) | NPC1RAB9ASMN1; SMN2LTA4HTPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020125546-A1 | CONNECTOR FOR USE IN ANTIBODY MEDICAMENT CONJUGATE AND APPLICATIONS OF CONNECTOR | 荣昌生物制药（烟台）有限公司 | 2020-06-25 | — | — | WO | disclosed |