Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 6/20 | 0.44 |
| ▸ | PTK6 | Q13882 | 4/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22124679 | 0.86 | TTK (0.44) | TTKPTK6BRAFSYKAURKB | |
| SCHEMBL22122923 | 0.86 | PTK6 (0.49) | TTKPTK6SYKPTK2AURKB | |
| SCHEMBL30171768 | 0.86 | PTK6 (0.49) | TTKPTK6SYKPTK2AURKB | |
| SCHEMBL22124823 | 0.85 | TTK (0.44) | TTKPTK6BRAFSYKRAD52 | |
| SCHEMBL30171592 | 0.85 | TTK (0.44) | TTKPTK6BRAFSYKRAD52 | |
| Hydrochloric Acid SCHEMBL22123544 | 0.85 | TTK (0.44) | TTKPTK6BRAFSYKAURKB | |
| SCHEMBL30172068 | 0.82 | FYN (0.52) | TTKRAD52FYNMCHR1ALK | |
| SCHEMBL22122904 | 0.82 | FYN (0.52) | TTKRAD52FYNMCHR1ALK | |
| SCHEMBL24112325 | 0.81 | TTK (0.43) | TTKPTK6BRAFRAD52FYN | |
| SCHEMBL30171838 | 0.81 | F10 (0.46) | TTKPTK6SYKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020126956-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |