Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 9/20 | 0.54 |
| ▸ | SMARCA4 | P51532 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22125283 | 0.83 | SMARCA2 (0.60) | SMARCA2SMARCA4HDAC4 | |
| SCHEMBL9984900 | 0.81 | BCHE (0.56) | MAPTNPC1RAB9ABCHEACHE | |
| SCHEMBL3760987 | 0.81 | POLB (0.56) | SMARCA2SMARCA4NPC1RAB9ABCHE | |
| SCHEMBL17804195 | 0.78 | SMARCA2 (0.64) | SMARCA2SMARCA4ARSMN1; SMN2 | |
| SCHEMBL3765780 | 0.78 | BCHE (0.41) | MAPTNPC1RAB9ABCHEMEN1 | |
| SCHEMBL13139726 | 0.77 | POLB (0.68) | SMARCA2SMARCA4MAPTNPC1RAB9A | |
| SCHEMBL5145795 | 0.76 | SMARCA2 (0.65) | SMARCA2SMARCA4ARMEN1LMNA | |
| SCHEMBL1501665 | 0.76 | SMARCA2 (0.57) | SMARCA2SMARCA4AR | |
| SCHEMBL9599834 | 0.76 | SMARCA2 (0.86) | SMARCA2SMARCA4MAPTNPC1RAB9A | |
| SCHEMBL10778464 | 0.74 | NPC1 (0.54) | MAPTNPC1RAB9AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020126968-A2 | UREA DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |