Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 8/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 11/20 | 0.35 |
| ▸ | JAK1 | P23458 | 10/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22139101 | 1.00 | PTK6 (0.40) | PTK6AURKBJAK2JAK1LCK | |
| SCHEMBL22124513 | 1.00 | PTK6 (0.40) | PTK6AURKBJAK2JAK1LCK | |
| Formic Acid SCHEMBL25174741 | 0.98 | PTK6 (0.39) | PTK6AURKBJAK2JAK1LCK | |
| SCHEMBL22124449 | 0.95 | PTK6 (0.42) | PTK6AURKBJAK2JAK1LCK | |
| SCHEMBL30177633 | 0.95 | PTK6 (0.42) | PTK6AURKBJAK2JAK1LCK | |
| SCHEMBL30177896 | 0.95 | PTK6 (0.42) | PTK6AURKBJAK2JAK1LCK | |
| SCHEMBL24910632 | 0.94 | PTK6 (0.40) | PTK6AURKBJAK2JAK1LCK | |
| SCHEMBL22123347 | 0.94 | PTK6 (0.40) | PTK6AURKBLCKTTK | |
| SCHEMBL22154796 | 0.93 | PTK6 (0.39) | PTK6AURKBJAK2JAK1LCK | |
| SCHEMBL22139104 | 0.93 | PTK6 (0.39) | PTK6AURKBJAK2JAK1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020126956-A1 | IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |