Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 17/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2208970 | 0.92 | GCK (0.58) | GCKL3MBTL1 | |
| SCHEMBL2214421 | 0.89 | GCK (0.59) | GCKL3MBTL1 | |
| SCHEMBL2211348 | 0.88 | GCK (0.59) | GCKL3MBTL1ALPLALPIALPG | |
| SCHEMBL12514253 | 0.88 | GCK (0.57) | GCKL3MBTL1ALPLALPIALPG | |
| SCHEMBL2212669 | 0.87 | GCK (0.57) | GCKL3MBTL1ALPLALPIALPG | |
| SCHEMBL2210696 | 0.86 | GCK (0.56) | GCKL3MBTL1ALPLALPIALPG | |
| SCHEMBL2213345 | 0.86 | GCK (0.59) | GCKL3MBTL1 | |
| SCHEMBL2213370 | 0.86 | GCK (0.73) | GCKL3MBTL1 | |
| SCHEMBL2212557 | 0.86 | GCK (0.73) | GCKL3MBTL1ALPLALPIALPG | |
| SCHEMBL2208913 | 0.86 | GCK (0.62) | GCKL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1598349-B1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | MSD KK (JP) | 2011-07-27 | — | — | EP | claimed |