SCHEMBL22157012

SCHEMBL22157012

Cc1ccc(-c2ccc3c4ccc(-c5ccc(C)cc5C)cc4n(-c4cc(-c5c(F)cccc5F)cc(-n5c6cc(-c7ccc(C)cc7C)ccc6c6ccc(-c7ccc(C)cc7C)cc65)c4C#N)c3c2)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE9A O76083 3/20 0.38
ALDH1A1 P00352 4/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
MAPT P10636 1/20 0.34
PDE1C Q14123 2/20 0.32
BIRC5 O15392 1/20 0.31
PRMT5 O14744 1/20 0.31
WDR77 Q9BQA1 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2B Q13224 1/20 0.31
CXCR2 P25025 1/20 0.31
PIK3R2 O00459 1/20 0.31
PDE3B Q13370 1/20 0.31
PDE3A Q14432 1/20 0.31
HPGD P15428 3/20 0.31
CYP2C9 P11712 2/20 0.31
CYP1A2 P05177 1/20 0.31
GAA P10253 2/20 0.31
TNKS O95271 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22157013 0.96 PDE9A (0.39) PDE9AALDH1A1MEN1KMT2AMAPT
SCHEMBL22157014 0.90 PDE9A (0.39) PDE9AALDH1A1MEN1KMT2AMAPT
SCHEMBL22158441 0.89 PDE9A (0.32) PDE9AALDH1A1MEN1KMT2AMAPT
SCHEMBL22156491 0.89 AR (0.39) PDE9AALDH1A1MEN1KMT2AMAPT
SCHEMBL22156441 0.89 PDE9A (0.38) PDE9AALDH1A1MEN1KMT2AMAPT
SCHEMBL22156607 0.88 PDE9A (0.37) PDE9AALDH1A1MEN1KMT2AMAPT
SCHEMBL22156484 0.87 AR (0.39) PDE9AALDH1A1MEN1KMT2AMAPT
SCHEMBL22158430 0.87 PDE9A (0.38) PDE9AALDH1A1MEN1KMT2AMAPT
SCHEMBL21898642 0.87 AR (0.38) PDE9AALDH1A1MEN1KMT2AMAPT
SCHEMBL22158399 0.86 BIRC5 (0.31) PDE9ABIRC5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200203628-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2020-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200203628-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, ORC3, OR51E2 PDE9A 4546/4885ALDH1A1 1882/4885MEN1 3687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.