SCHEMBL22157376

SCHEMBL22157376

C=CCCCN(CC)CCCCCC

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.60
ALDH1A1 P00352 1/20 0.52
KCNH2 Q12809 11/20 0.44
DNM1 Q05193 3/20 0.39
PLA2G1B P04054 1/20 0.38
PLA2G2A P14555 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22157450 0.98 TSHR (0.56) TSHRALDH1A1KCNH2DNM1PLA2G1B
SCHEMBL22157402 0.91 TSHR (0.56) TSHRALDH1A1KCNH2PLA2G1BPLA2G2A
SCHEMBL22157388 0.91 TSHR (0.65) TSHRALDH1A1KCNH2DNM1
SCHEMBL22157379 0.91 TSHR (0.65) TSHRALDH1A1KCNH2DNM1
SCHEMBL22157441 0.89 TSHR (0.62) TSHRALDH1A1KCNH2DNM1
SCHEMBL20365703 0.89 TSHR (0.50) TSHRALDH1A1KCNH2DNM1PLA2G1B
SCHEMBL22157404 0.89 TSHR (0.61) TSHRALDH1A1KCNH2DNM1
SCHEMBL27334473 0.88 TSHR (0.54) TSHRALDH1A1KCNH2
SCHEMBL22157536 0.88 TSHR (0.60) TSHRALDH1A1KCNH2DNM1
SCHEMBL23679028 0.87 TSHR (0.73) TSHRALDH1A1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3884019-A1 HOME CARE COMPOSITIONS Colgate-Palmolive Company (US) 2021-09-29 EP disclosed
CN-113227340-A Home care compositions 高露洁-棕榄公司 2021-08-06 CN disclosed
US-11008533-B2 Home care compositions COLGATE-PALMOLIVE COMPANY (US) 2021-05-18 US disclosed
US-20200208081-A1 HOME CARE COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 2020-07-02 US disclosed
WO-2020139335-A1 HOME CARE COMPOSITIONS COLGATE-PALMOLIVE COMPANY (US) 2020-07-02 WO disclosed