Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169975 | 1.00 | MAPT (0.51) | MAPTCYP3A4CYP19A1LMNATP53 | |
| SCHEMBL2214289 | 0.79 | KMT2A (0.48) | MAPTCYP19A1LMNATP53HSP90AA1 | |
| SCHEMBL1967461 | 0.79 | KMT2A (0.48) | MAPTCYP19A1LMNATP53HSP90AA1 | |
| SCHEMBL11366095 | 0.78 | MAPT (0.77) | MAPTCYP3A4CYP19A1LMNAHSP90AA1 | |
| SCHEMBL1965569 | 0.78 | MAPT (0.53) | MAPTCYP3A4CYP19A1HSP90AA1KMT2A | |
| SCHEMBL10771521 | 0.76 | MAPT (0.55) | MAPTCYP3A4LMNAHSP90AA1KMT2A | |
| SCHEMBL1966676 | 0.76 | MAPT (0.54) | MAPTCYP3A4CYP19A1LMNAHSP90AA1 | |
| SCHEMBL11641005 | 0.76 | MAPT (0.56) | MAPTCYP3A4CYP19A1HSP90AA1KMT2A | |
| SCHEMBL12415427 | 0.73 | MAPT (0.60) | MAPTCYP3A4CYP19A1LMNAHSP90AA1 | |
| SCHEMBL3121057 | 0.72 | MAPT (0.53) | MAPTCYP3A4LMNAHSP90AA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110177950-A1 | Imidazole and Triazole Compounds, Their Use and Agents Containing the Same | BASF SE (DE) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110177950-A1 | Imidazole and Triazole Compounds, Their Use and Agents Containing the Same | COX4I1, CYP2C19, CYP3A43 | MAPT 513/4885CYP3A4 4/4885CYP19A1 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.