Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 11/20 | 0.45 |
| ▸ | MAPKAPK5 | Q8IW41 | 2/20 | 0.40 |
| ▸ | TTK | P33981 | 7/20 | 0.40 |
| ▸ | LCK | P06239 | 5/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123920 | 0.90 | PTK6 (0.46) | PTK6MAPKAPK5TTKLCKAURKB | |
| SCHEMBL22125340 | 0.90 | PTK6 (0.47) | PTK6MAPKAPK5TTKLCKAURKB | |
| SCHEMBL22125271 | 0.90 | PTK6 (0.47) | PTK6MAPKAPK5TTKLCKAURKB | |
| SCHEMBL30201986 | 0.90 | PTK6 (0.47) | PTK6MAPKAPK5TTKLCKAURKB | |
| SCHEMBL22124582 | 0.90 | PTK6 (0.47) | PTK6MAPKAPK5TTKLCKAURKB | |
| SCHEMBL24870735 | 0.90 | PTK6 (0.47) | PTK6MAPKAPK5TTKLCKAURKB | |
| Hydrochloric Acid SCHEMBL30172098 | 0.89 | PTK6 (0.46) | PTK6MAPKAPK5TTKLCKAURKB | |
| Hydrochloric Acid SCHEMBL30171999 | 0.89 | PTK6 (0.46) | PTK6MAPKAPK5TTKLCKAURKB | |
| SCHEMBL22125501 | 0.88 | PTK6 (0.45) | PTK6MAPKAPK5TTKLCKAURKB | |
| SCHEMBL22154767 | 0.86 | PTK6 (0.44) | PTK6MAPKAPK5TTKLCKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |
| WO-2020126953-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-25 | — | — | WO | disclosed |