SCHEMBL22161985

SCHEMBL22161985

CCCC1CCC(C2CCC(c3ccc(OCC)c(F)c3)CC2)CC1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 4/20 0.51
CYP2C9 P11712 1/20 0.42
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
LMNA P02545 1/20 0.40
MEN1 O00255 1/20 0.40
MAPK1 P28482 1/20 0.40
KMT2A Q03164 1/20 0.40
PDE4A P27815 2/20 0.35
HTT P42858 1/20 0.33
PDE5A O76074 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
ESR2 Q92731 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NAAA Q02083 1/20 0.32
HPGD P15428 1/20 0.32
KCNQ3 O43525 1/20 0.32
KCNQ2 O43526 1/20 0.32
TUBB1 Q9H4B7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11060799 0.96 KDM1A (0.55) KDM1ACYP2C9ALDH1A1MAPTLMNA
SCHEMBL11060802 0.96 KDM1A (0.55) KDM1ACYP2C9ALDH1A1MAPTLMNA
SCHEMBL18310514 0.91 KDM1A (0.41) KDM1ACYP2C9ALDH1A1MAPTLMNA
SCHEMBL13128375 0.91 KDM1A (0.41) KDM1ACYP2C9ALDH1A1MAPTLMNA
SCHEMBL10982370 0.88 KDM1A (0.52) KDM1ACYP2C9ALDH1A1MAPTLMNA
SCHEMBL10982364 0.88 KDM1A (0.52) KDM1ACYP2C9ALDH1A1MAPTLMNA
SCHEMBL10979273 0.87 KDM1A (0.51) KDM1ACYP2C9ALDH1A1MAPTLMNA
SCHEMBL10979270 0.87 KDM1A (0.51) KDM1ACYP2C9ALDH1A1MAPTLMNA
SCHEMBL10975492 0.87 KDM1A (0.44) KDM1ACYP2C9ALDH1A1MAPTLMNA
SCHEMBL13128378 0.87 KDM1A (0.44) KDM1ACYP2C9ALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200199451-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2020-06-25 US disclosed