Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MGAM | O43451 | 13/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27917533 | 0.92 | MEN1 (0.74) | MEN1KMT2AMGAM | |
| SCHEMBL27962910 | 0.89 | MEN1 (0.63) | MEN1KMT2AMGAMMITFPOLB | |
| SCHEMBL27917615 | 0.89 | MEN1 (0.63) | MEN1KMT2AMGAMMITFPOLB | |
| SCHEMBL27962944 | 0.89 | MEN1 (0.63) | MEN1KMT2AMGAMMITFPOLB | |
| SCHEMBL29817694 | 0.89 | MEN1 (0.63) | MEN1KMT2AMGAMMITFPOLB | |
| SCHEMBL28819658 | 0.85 | MGAM (0.65) | MEN1KMT2AMGAMMITFPOLB | |
| SCHEMBL30607045 | 0.85 | HDAC1 (0.68) | MEN1KMT2AMGAM | |
| SCHEMBL28017777 | 0.85 | HDAC1 (0.68) | MEN1KMT2AMGAM | |
| SCHEMBL27962879 | 0.85 | MEN1 (0.60) | MEN1KMT2AMGAMMITFPOLB | |
| SCHEMBL28033063 | 0.85 | MEN1 (0.63) | MEN1KMT2AMGAMMITFPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1634881-B1 | HARMINE DERIVATIVES, INTERMEDIATES USED IN THEIR PREPARATION, PREPARATION PROCESSES AND USE THEREOF | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD (CN) | 2011-07-27 | — | — | EP | claimed |