Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 3/20 | 0.34 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.34 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17459639 | 0.89 | MME (0.41) | CTSBHPGDSMME | |
| SCHEMBL17459640 | 0.89 | MME (0.41) | CTSBHPGDSMME | |
| SCHEMBL16295098 | 0.89 | MME (0.41) | CTSBHPGDSMME | |
| SCHEMBL22384332 | 0.88 | KLKB1 (0.44) | RAB9AKLKB1 | |
| SCHEMBL15019919 | 0.86 | MME (0.42) | HPGDSMME | |
| SCHEMBL15019922 | 0.86 | MME (0.42) | HPGDSMME | |
| SCHEMBL22167206 | 0.85 | TDP1 (0.41) | CTSBKLKB1CTSSCTSKMME | |
| SCHEMBL17459588 | 0.85 | TDP1 (0.41) | CTSBKLKB1CTSSCTSKMME | |
| SCHEMBL16305782 | 0.85 | TDP1 (0.41) | CTSBKLKB1CTSSCTSKMME | |
| SCHEMBL17459587 | 0.85 | TDP1 (0.41) | CTSBKLKB1CTSSCTSKMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |