Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22167668 | 0.80 | CYP2C9 (0.48) | USP2CYP2C9CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL2081988 | 0.78 | KMT2A (0.54) | USP2CYP2C9CYP1A2CYP2D6KMT2A | |
| SCHEMBL15451913 | 0.77 | CYP1A2 (0.53) | USP2CYP2C9CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL208812 | 0.74 | TSHR (0.61) | USP2CYP2C9CYP1A2CYP2C19KMT2A | |
| SCHEMBL18563361 | 0.73 | CYP2C9 (0.50) | USP2CYP2C9CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL26806776 | 0.73 | CYP2C9 (0.50) | USP2CYP2C9CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL12437235 | 0.73 | CYP2C9 (0.46) | USP2CYP2C9CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL11578213 | 0.72 | TSHR (0.64) | USP2CYP2C9CYP1A2CYP2C19KMT2A | |
| SCHEMBL30562146 | 0.72 | FFAR3 (0.50) | USP2CYP2C9CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL17176084 | 0.71 | USP2 (0.51) | USP2CYP2C9CYP1A2CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020135771-A1 | HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2020-07-02 | — | — | WO | disclosed |