⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12684880 | 0.76 | — | — | |
| SCHEMBL20878845 | 0.75 | — | — | |
| SCHEMBL22270751 | 0.73 | — | — | |
| SCHEMBL20878840 | 0.72 | — | — | |
| SCHEMBL25465182 | 0.71 | — | — | |
| SCHEMBL19413807 | 0.70 | PPARA (0.33) | — | |
| SCHEMBL20880172 | 0.70 | — | — | |
| SCHEMBL21027462 | 0.69 | — | — | |
| SCHEMBL19542368 | 0.69 | — | — | |
| SCHEMBL14864826 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230144841-A1 | INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN | Praxis Biotech LLC (US) | 2023-05-11 | — | — | US | disclosed |
| US-20200206216-A1 | INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN | Praxis Biotech LLC | 2020-07-02 | — | — | US | disclosed |