Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31600826 | 0.79 | KDM4E (0.40) | CYP1A2LRRK2TLR8KDM4ENSD2 | |
| SCHEMBL18081458 | 0.77 | KDM4E (0.33) | HTTKDM4ENSD2ALDH1A1MAPT | |
| SCHEMBL17875687 | 0.77 | PRNP (0.42) | HTTLMNAKDM4ENSD2ALDH1A1 | |
| SCHEMBL3978933 | 0.75 | NQO2 (0.41) | HTTLMNAKDM4ENSD2ALDH1A1 | |
| SCHEMBL25317472 | 0.74 | TLR8 (0.42) | EPRS1TLR8 | |
| SCHEMBL31210637 | 0.74 | KDM4E (0.33) | KDM4ENSD2ALDH1A1MAPT | |
| SCHEMBL29303414 | 0.74 | NMT1 (0.42) | HTTKDM4ENSD2ALDH1A1MAPT | |
| SCHEMBL25227561 | 0.74 | NSD1 (0.42) | HTTLMNAKDM4ENSD2ALDH1A1 | |
| SCHEMBL31210645 | 0.74 | KDM4E (0.33) | KDM4ENSD2ALDH1A1MAPT | |
| SCHEMBL26664175 | 0.73 | KDM4E (0.31) | KDM4ENSD2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111547-A1 | 2,3-DIHYDROPYROLLOPYRIDINE CARBOXAMIDE COMPOUNDS AND METHODS OF USE THEREOF | RGENTA THERAPEUTICS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |
| CN-117769546-A | Allosteric ketene inhibitors of phosphoinositide 3-kinase (PI 3K) for the treatment of disease | 佩特拉制药公司 | 2024-03-26 | — | — | CN | disclosed |
| WO-2020135507-A1 | POLYSUBSTITUTED ANILINOPYRIMIDINE DERIVATIVE AND PREPARATION METHOD AND APPLICATION THEREOF | 杭州百新生物医药科技有限公司 | 2020-07-02 | — | — | WO | disclosed |