Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRF | P10586 | 2/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 18/20 | 0.41 |
| ▸ | PPARG | P37231 | 13/20 | 0.41 |
| ▸ | PPARD | Q03181 | 9/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1750019 | 1.00 | PTPRF (0.41) | PTPRFPTPN2PTPN1PPARAPPARG | |
| SCHEMBL1749562 | 0.93 | PPARA (0.43) | PTPRFPTPN2PTPN1PPARAPPARG | |
| SCHEMBL5761770 | 0.91 | PTPRF (0.36) | PTPRFPTPN2PTPN1PPARAPPARG | |
| SCHEMBL5760611 | 0.88 | PPARA (0.40) | PTPRFPTPN2PTPN1PPARAPPARG | |
| SCHEMBL1749609 | 0.85 | PTPRF (0.42) | PTPRFPTPN2PTPN1PPARAPPARG | |
| SCHEMBL1750606 | 0.85 | HDAC1 (0.34) | PPARAPPARGPPARD | |
| SCHEMBL1750609 | 0.85 | HDAC1 (0.34) | PPARAPPARGPPARD | |
| SCHEMBL2220220 | 0.84 | MME (0.41) | — | |
| SCHEMBL1750293 | 0.84 | MME (0.41) | — | |
| SCHEMBL1749931 | 0.83 | PPARA (0.42) | PTPRFPTPN2PTPN1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638964-B1 | NOVEL COMPOUNDS THAT MODULATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2011-07-27 | — | — | EP | claimed |