Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 0.58 |
| ▸ | JAK2 | O60674 | 2/20 | 0.46 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28422674 | 0.84 | NTRK1 (0.68) | NTRK1JAK2NTRK3 | |
| SCHEMBL29541946 | 0.84 | NTRK1 (0.68) | NTRK1JAK2NTRK3 | |
| SCHEMBL22175069 | 0.84 | NTRK1 (0.68) | NTRK1JAK2NTRK3 | |
| SCHEMBL18875082 | 0.83 | NTRK1 (0.80) | NTRK1JAK2NTRK3 | |
| SCHEMBL22175157 | 0.83 | NTRK1 (0.61) | NTRK1JAK2NTRK3 | |
| SCHEMBL29542542 | 0.83 | NTRK1 (0.61) | NTRK1JAK2NTRK3 | |
| SCHEMBL17820710 | 0.81 | NTRK1 (0.65) | NTRK1JAK2 | |
| SCHEMBL17820882 | 0.81 | NTRK1 (0.65) | NTRK1JAK2 | |
| SCHEMBL30151383 | 0.81 | NTRK1 (0.65) | NTRK1JAK2 | |
| SCHEMBL29618154 | 0.81 | NTRK1 (0.58) | NTRK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111362946-A | Pharmaceutical compound and composition and application thereof | 上海度德医药科技有限公司 | 2020-07-03 | — | — | CN | disclosed |
| WO-2020135203-A1 | PHARMACEUTICAL COMPOUND, COMPOSITION THEREOF, AND APPLICATION | 上海度德医药科技有限公司 | 2020-07-02 | — | — | WO | disclosed |