Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | KCNN3 | Q9UGI6 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22164199 | 0.99 | PDE10A (0.36) | PDE10AKCNN3 | |
| Hydrochloric Acid SCHEMBL22164200 | 0.99 | PDE10A (0.36) | PDE10AKCNN3 | |
| SCHEMBL22176343 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL22164227 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL22164226 | 0.77 | — | — | |
| SCHEMBL22175837 | 0.77 | — | — | |
| SCHEMBL1934522 | 0.71 | PDE10A (0.48) | PDE10A | |
| SCHEMBL22686367 | 0.70 | PDE10A (0.44) | PDE10AKCNN3 | |
| SCHEMBL22176046 | 0.70 | KDM4E (0.42) | PDE10AKCNN3 | |
| SCHEMBL22175838 | 0.66 | PDE10A (0.40) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020138015-A1 | PYRAZOLO[1,5-A]PYRIMIDINE MACROCYCLIC COMPOUND | 大正製薬株式会社 | 2020-07-02 | — | — | WO | disclosed |