Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416508 | 0.92 | HPGD (0.51) | HPGDKDM4EPKMRECQLEPHX1 | |
| SCHEMBL22181462 | 0.89 | NR1H2 (0.46) | HPGDKDM4EPKMRECQLEPHX1 | |
| SCHEMBL24510266 | 0.86 | HPGD (0.54) | HPGDKDM4EPKMRECQLEPHX1 | |
| SCHEMBL31271524 | 0.85 | NR1H2 (0.52) | HPGDKDM4EPKMRECQLCHRM1 | |
| SCHEMBL22181207 | 0.83 | HPGD (0.47) | HPGDKDM4EPKMRECQLCHRM1 | |
| SCHEMBL1899642 | 0.83 | NR1H2 (0.47) | HPGDKDM4EPKMRECQLEPHX1 | |
| SCHEMBL18497462 | 0.83 | NR1H2 (0.47) | HPGDKDM4EPKMRECQLEPHX1 | |
| SCHEMBL25313452 | 0.83 | NR1H2 (0.47) | HPGDKDM4EPKMRECQLEPHX1 | |
| SCHEMBL31270977 | 0.82 | HPGD (0.48) | HPGDKDM4ERECQLCHRM1EPHX1 | |
| SCHEMBL4036153 | 0.81 | HPGD (0.50) | HPGDKDM4EPKMRECQLCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020138398-A1 | NOVEL COMPOUND INHIBITING LYSINE-SPECIFIC DEMETHYLATING ENZYME 1, METHOD FOR PRODUCING SAME, AND USE OF SAME | 国立研究開発法人理化学研究所 | 2020-07-02 | — | — | WO | disclosed |