Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL28281552 | 0.84 | TSHR (0.43) | KDM4EMAPTALOX15TSHRALDH1A1 | |
| Sulfuric Acid SCHEMBL30490011 | 0.84 | TSHR (0.43) | KDM4EMAPTALOX15TSHRALDH1A1 | |
| Sulfuric Acid SCHEMBL18038939 | 0.80 | TSHR (0.42) | KDM4EMAPTALOX15TSHRALDH1A1 | |
| Sulfuric Acid SCHEMBL11872534 | 0.77 | TP53 (0.50) | KDM4EMAPTALOX15TSHRALDH1A1 | |
| Sulfuric Acid SCHEMBL6736605 | 0.77 | TP53 (0.50) | KDM4EMAPTALOX15TSHRALDH1A1 | |
| Sulfuric Acid SCHEMBL7606689 | 0.77 | TSHR (0.38) | KDM4EMAPTALOX15TSHRALDH1A1 | |
| Sulfuric Acid SCHEMBL7606683 | 0.77 | TSHR (0.38) | KDM4EMAPTALOX15TSHRALDH1A1 | |
| Sulfuric Acid SCHEMBL31239129 | 0.77 | TSHR (0.38) | KDM4EMAPTALOX15TSHRALDH1A1 | |
| SCHEMBL124278 | 0.75 | — | — | |
| SCHEMBL28365343 | 0.75 | MAPT (0.44) | KDM4EMAPTALOX15TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120850-B2 | Biosensor for detection and visualisation of single-stranded DNA | MEDICAL RESEARCH COUNCIL (GB) | 2015-09-01 | — | — | US | disclosed |
| EP-2170937-B1 | LABELED SINGLE-STRAND DNA-BINDING PROTEIN AND ITS USE IN A BIOSENSOR FOR DETECTION AND VISUALISATION OF SINGLE-STRANDED DNA | MEDICAL RES COUNCIL (GB) | 2014-04-30 | — | — | EP | disclosed |
| US-20110177501-A1 | BIOSENSOR FOR DETECTION AND VISUALISATION OF SINGLE-STRANDED DNA | MEDICAL RESEARCH COUNCIL | 2011-07-21 | — | — | US | disclosed |
| EP-2170937-A1 | LABELED SINGLE-STRAND DNA-BINDING PROTEIN AND ITS USE IN A BIOSENSOR FOR DETECTION AND VISUALISATION OF SINGLE-STRANDED DNA | Medical Research Council (GB) | 2010-04-07 | — | — | EP | disclosed |
| WO-2008152379-A1 | LABELED SINGLE-STRAND DNA-BINDING PROTEIN AND ITS USE IN A BIOSENSOR FOR DETECTION AND VISUALISATION OF SINGLE-STRANDED DNA | MEDICAL RESEARCH COUNCIL (GB) | 2008-12-18 | — | — | WO | disclosed |
| EP-0113094-B1 | TEST DEVICE AND PROCESS FOR THE DETECTION OF THIOLS | BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) | 1988-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110177501-A1 | BIOSENSOR FOR DETECTION AND VISUALISATION OF SINGLE-STRANDED DNA | SSBP1, SSB, DDB1 | KDM4E 3342/4885MAPT 4151/4885ALOX15 4874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.