Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 1/20 | 0.78 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.78 |
| ▸ | ST6GAL1 | P15907 | 2/20 | 0.75 |
| ▸ | GPBAR1 | Q8TDU6 | 9/20 | 0.74 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.74 |
| ▸ | CASP7 | P55210 | 3/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | BLM | P54132 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | VDR | P11473 | 2/20 | 0.72 |
| ▸ | USP2 | O75604 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | MDM4 | O15151 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5057516 | 1.00 | OSBP (0.78) | OSBPOSBP2ST6GAL1GPBAR1NR1H4 | |
| SCHEMBL231519 | 1.00 | OSBP (0.78) | OSBPOSBP2ST6GAL1GPBAR1NR1H4 | |
| SCHEMBL22894424 | 1.00 | OSBP (0.78) | OSBPOSBP2ST6GAL1GPBAR1NR1H4 | |
| SCHEMBL5057515 | 1.00 | OSBP (0.78) | OSBPOSBP2ST6GAL1GPBAR1NR1H4 | |
| SCHEMBL17817650 | 1.00 | OSBP (0.78) | OSBPOSBP2ST6GAL1GPBAR1NR1H4 | |
| SCHEMBL14601809 | 1.00 | OSBP (0.78) | OSBPOSBP2ST6GAL1GPBAR1NR1H4 | |
| SCHEMBL1252834 | 1.00 | OSBP (0.78) | OSBPOSBP2ST6GAL1GPBAR1NR1H4 | |
| SCHEMBL21946830 | 0.93 | GPBAR1 (0.76) | OSBPOSBP2ST6GAL1GPBAR1NR1H4 | |
| SCHEMBL24104272 | 0.91 | OSBP (0.78) | OSBPOSBP2ST6GAL1GPBAR1NR1H4 | |
| SCHEMBL24710285 | 0.91 | OSBP (0.78) | OSBPOSBP2ST6GAL1GPBAR1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020136292-A1 | COMPOUNDS OF PHARMACEUTICAL INTEREST | UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (ES) | 2020-07-02 | — | — | WO | disclosed |